After installing an in-place upgrade to Windows 10 you may receive the following dialog when launching Macrium Reflect v5 or v6:
An update is available to correct this issue. Please download and install the latest installer for your edition of Macrium Reflect by following the instructions here: Installing Macrium Reflect
Macrium Reflect v5 keys begin with the number '1' and v6 keys begin with '3'.
Please note that you do not need to uninstall Macrium Reflect before installing this upgrade.Your existing installation will be upgraded to the latest release and your settings will be preserved.